Frontal fibrosing alopecia. Authoritative facts about the skin from DermNet New Zealand. Frontal fibrosing alopecia is a disorder resulting in hair loss at the temples and front of the scalp. Learn about the causes and treatment of FFA. BackgroundFrontal fibrosing alopecia is considered a particular clinical form of lichen planopilaris that primarily involves the scalp hair over the frontal hai.

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The rate of hair loss tends to vary from person to person. Acute hair loss on the limbs in frontal fibrosing alopecia: Frontal fibrosing alopecia is a specific form of scarring alopecia that affects the frontal hairline, most often in postmenopausal women. Self-skin examination New smartphone apps to check your skin Learn more Sponsored content.

Hair on her limbs had not been present for 5 years. The clinical features of frontal fibrosing alopecia are characteristic. Pirmez, Rodrigo et al. This treatment may need to be repeated. Disease definition Frontal fibrosing alopecia FFA is a rare variant a,opecia lichen planopilaris see this term characterized by symmetrical, progressive, band-like anterior hair loss of the scalp.

There are treatments that help to slow down or halt further hair loss in some people. Powered By Decision Support in Medicine. J Am Acad Dermatol.

A skin biopsy examination in the laboratory may help to make or confirm the diagnosis. Purchase access Subscribe to JN Learning for one year. Sign in to save your search Sign in to your personal account. The facial skin specimen showed intense lymphoplasmocytic infiltrate with complete destruction of the follicle and only remnants of the piloerector muscle and sebaceous gland Figure 2 C.

The induction of this reaction at the frontal hairline may subsequently trigger a more widespread destruction of the eyebrows and hair follicles at other sites. Diagnosis confirmation The differential diagnosis of FFA includes: Etiology The etiology of FFA remains unknown.


Sign in to access your subscriptions Sign in to your personal account. Back to top Article Information. Tufted groups of hairs and varioliform scars may emerge. Lupus is rarely confined to the alopecka hairline or associated with total loss of the eyebrows.

Your local hospital orthotic surgical appliances department will be able to advise you on the range of hairpieces available on the NHS. The finding dibrosing gross interfollicular scarring, panfollicular lymphocytic inflammation, or involvement of the interfollicular epidermis in a biopsy should prompt a search for an alternate alopscia of scarring alopecia that may mimic FFA.

There are no known systemic associations in FFA, and currently the process is best classified as a variant of lichen planopilaris, with a distinct clinical presentation linked by an identical histopathology. Donati, Molina, and Doche. The process appears to be particularly linked to elderly women, in the years following menopause, and has a distinct pattern of distribution. Whether current therapy ultimately alters the course or severity of A,opecia has not been established.

Frontal fibrosing alopecia | DermNet NZ

Concomitant involvement of vellus at different body sites has recently been reported. Topical corticosteroids, topical tacrolimus, or topical retinoids have not shown benefit.

In alopecia areata, multifocal patches of alopecia are often present, and the marginal involvement is often more prominent over the occipital and parietal areas. Create a free personal account to download free article PDFs, sign up for alerts, and more.

Drafting of the manuscript: J Am Acad Dermatol ; The areas of fibrosing alopecia do not appear grossly scarred and there is an absence of mottled pigmentation, marked scaling, pustules, or groups of hairs forming tufts.

Facial Papules in Frontal Fibrosing Alopecia: Where to do research?

Frontal fibrosing alopecia

It will usually require a trial of months. Thesemedicines are chiefly used to help reduce inflammation and not for their antibiotic action. Biopsies of both the frontal hairline and preauricular region were performed.

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The exact cause of frontal fibrosing alopecia is unknown. You must be a registered member of Dermatology Advisor to post a comment. Back Why do research alopeci dermatology? Unlike the usual noninflammatory clinical presentation of vellus involvement over other body areas, fibrosinh vellus involvement can lead to surface changes that may be recognized both by patients and dermatologists.

Frontal fibrosing alopecia is not an inherited condition, although occasionally it has been reported to alopeci a number of people in the same family. Frontal fibrosing alopecia was originally described in postmenopausal women, but now has been seen in premenopousal women.

Expanding the spectrum of frontal fibrosing alopecia: A small scar is left at the site of allpecia biopsy. It is important to avoid too much tension on any hair when this is done. FFA occurs mostly in white postmenopausal women but can occur in premenopausal women, men, and people of other ethnicities.

The lichenoid reaction in FFA targets and destroys the follicular sheaths and stem cell region, but spares the interfollicular epidermis and also the lower follicle and hair bulb region.


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Less frequently, eyelashes and hairs in the axilla or pubic area can also be affected. Further studies are needed to determine the prevalence of skin involvement frontall patients with FFA.

J Eur Acad Dermatol Venereol. Frontal fibrosing alopecia may cause no symptoms at all or may cause an itchy, painful or burning sensation in a band across the frontal hairline.